APC Anti-Rat CD161 Antibody[3.2.3]
Product Specifications
Background
CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.
Abbreviation
CD161
Gene ID
25192;362443;678513
UniProt
P27471; A4KWA1; Q5NKN4; Q5NKN2
Host
Mouse
Reactivity
Rat
Target
CD161a/CD161bNKR-P1a/KLRB1a; NKR-P1
Clonality
Monoclonal
Clone
3.2.3
Conjugation
APC
Applications
FCM
Field of Research
Cell Biology; Immunology; Innate Immunity; Signal Transduction
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
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