PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61]
Product Specifications
Background
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced) /155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Abbreviation
CD163
Gene ID
9332
UniProt
Q86VB7
Host
Mouse
Reactivity
Human
Target
ED2 (rat) Hemoglobin/Haptoglobin Complex ReceptorM130RM3/1macrophage-associated antigenp155; GHI/61
Clonality
Monoclonal
Clone
GHI/61
Conjugation
PerCP/Cyanine 5.5
Applications
FCM
Field of Research
Cell Biology; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.sciencedirect.com/science/article/pii/S1567576923008287
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
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