PE Anti-Human/Mouse KLRG-1 Antibody[2F1]
Product Specifications
Background
Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag) . KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG5 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
Abbreviation
KLRG-1
Gene ID
10219;50928
UniProt
Q96E93; O88713
Host
Syrian Hamster
Reactivity
Human; Mouse
Target
2F1-Ag; MAFA
Clonality
Monoclonal
Clone
2F1
Conjugation
PE
Applications
FCM
Field of Research
Immunology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Syrian Hamster IgG
Available Sizes
Curated Selection
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