PE Anti-Human CD133 Antibody[W6B3C1]
Product Specifications
Background
CD133, also known as Prominin-1 and AC133 antigen, is a 120 kD pentaspan glycoprotein with 5 transmembrane domains. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cells and some embryonic epithelia. Later on, CD133 was found on other stem cells, including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to stem cells for normal tissue, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. Although the biological function of CD133 is not completely understood, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.
Abbreviation
CD133
Gene ID
8842
UniProt
O43490
Host
Mouse
Reactivity
Human
Target
Prominin-1; AC133; Antigen AC133; CD133; CORD; CORD12; Hematopoietic stem cell antigen; MCDR; MCDR2; MSTP; MSTP061; OTTHUMP00000217744; OTTHUMP00000217745; PROM; PROM1; PROML; PROML1; Prominin-1; RP41; STGD; STGD4; hProminin
Clonality
Monoclonal
Clone
W6B3C1
Conjugation
PE
Applications
FCM
Field of Research
Cancer Biomarkers; Cell Biology; Immuno-Oncology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://pmc.ncbi.nlm.nih.gov/articles/PMC11866075/
Citation 02
https://www.sciencedirect.com/science/article/pii/S2667394025000048
Citation 03
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11218792/
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
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