PE/Cyanine7 Anti-Mouse CD200/OX2 Antibody[OX-90]
Product Specifications
Background
CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons) ; but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R) . The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.
Abbreviation
CD200
Gene ID
4345
UniProt
O54901
Host
Rat
Reactivity
Mouse
Target
MRC; OX-2; OX-2 membrane glycoprotein
Clonality
Monoclonal
Clone
OX-90
Conjugation
PE/Cyanine 7
Applications
FCM
Field of Research
Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers
Concentration
0.2 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/dmrfl0
Product MSDS
https://789.bio/eb/4KK4WP
Recommended Usage
6
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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