PE Anti-Human CD80 Antibody[2D10]

Product Specifications

Background

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Abbreviation

CD80

Gene ID

941

UniProt

P33681

Host

Mouse

Reactivity

Human

Target

B7BB1; B7-1; T-lymphocyte activation antigen CD80

Clonality

Monoclonal

Clone

2D10

Conjugation

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S1756464625001239

Citation 02

https://www.hindawi.com/journals/bmri/2022/3946754/

Citation 03

https://link.springer.com/article/10.1007/s11033-025-10517-z

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GTR15235428 1 Vial

Lentiviral mouse Mospd2 shRNA (UAS) - Lentiviral mouse Mospd2 shRNA (UAS, RFP) (100)

Ask

View Details

BS46707-01 50 µL

HBEGF Recombinant Rabbit mAb

Ask

View Details

BS46707-02 100 µL

HBEGF Recombinant Rabbit mAb

Ask

View Details

PH300495 10 µg

CDK1 (NM_001786) Human Mass Spec Standard

Ask

View Details

GTR15270483 1 Vial

Lentiviral mouse Prpf40a shRNA (UAS) - Lentiviral mouse Prpf40a shRNA (UAS, iRFP) (100)

Ask

View Details

274479-01 25 mg

(-) - (5aS,10bR) -5a,10b-Dihydro-2- (2,4,6-trimethylphenyl) -4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium Chloride Monohydrate

Ask

View Details