Purified Anti-Human CD3 Antibody[UCHT1]
Selected Variant
E-AB-F1230A-01
Size: 25 µg
Product Specifications
Background
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.
Abbreviation
CD3
Gene ID
916
UniProt
P07766
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD3 protein
Target
CD3E; CD3e; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E
Clonality
Monoclonal
Clone
UCHT1
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Citation 01
https://link.springer.com/article/10.1186/s12967-024-04931-3
Recommended Usage
6
Isotype
Mouse IgG1, κ
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