FITC Anti-Rat CD45 Antibody[OX-1]
Product Specifications
Background
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA) . It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.
Abbreviation
CD45
Gene ID
19265
UniProt
P04157
Host
Mouse
Reactivity
Rat
Target
LCALy-5T200; Leukocyte common antigen; Ptprc; Receptor-type tyrosine-protein phosphatase C
Clonality
Monoclonal
Clone
OX-1
Conjugation
FITC
Applications
FCM
Field of Research
Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://link.springer.com/article/10.1186/s13287-022-03018-4
Citation 02
https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8411131/
Citation 03
https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8411131/
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Documents
Curated Selection
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