PerCP/Cyanine5.5 Anti-Rat CD45 Antibody[OX-1]
Product Specifications
Background
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA) . It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.
Abbreviation
CD45
Gene ID
19265
UniProt
P04157
Host
Mouse
Reactivity
Rat
Target
LCALy-5T200; Leukocyte common antigen; Ptprc; Receptor-type tyrosine-protein phosphatase C
Clonality
Monoclonal
Clone
OX-1
Conjugation
PerCP/Cyanine 5.5
Applications
FCM
Field of Research
Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://onlinelibrary.wiley.com/doi/abs/10.1111/jpi.70046
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940178-100 1x 100 µL
CD50 (ICAM-3) (186-2G9), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040096-500 1x 500 µL
Histone H1 (AE-4), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471102-100 1x 100 µL
Cdc20 (CDC20/1102), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940159-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (GP1.4), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details