PerCP/Cyanine5.5 Anti-Rat CD45 Antibody[OX-1]

Product Specifications

Background

CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA) . It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

Abbreviation

CD45

Gene ID

19265

UniProt

P04157

Host

Mouse

Reactivity

Rat

Target

LCALy-5T200; Leukocyte common antigen; Ptprc; Receptor-type tyrosine-protein phosphatase C

Clonality

Monoclonal

Clone

OX-1

Conjugation

PerCP/Cyanine 5.5

Applications

FCM

Field of Research

Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://onlinelibrary.wiley.com/doi/abs/10.1111/jpi.70046

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

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