FITC Anti-Rat CD44H Antibody[OX-49]

Product Specifications

Background

CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Abbreviation

CD44H

Gene ID

12505

UniProt

P26051

Host

Mouse

Reactivity

Rat

Target

CD44sH-CAM; CD44H; Pgp-1

Clonality

Monoclonal

Clone

OX-49

Conjugation

FITC

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Immunology; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S2213231723000502

Citation 02

https://www.sciencedirect.com/science/article/pii/S0168365924006643

Citation 03

https://www.nature.com/articles/s41401-023-01066-x

Citation 04

https://www.sciencedirect.com/science/article/pii/S1567576923015175

Citation 05

https://www.sciencedirect.com/science/article/pii/S0006295224006944

Citation 06

https://www.mdpi.com/2218-273X/15/3/316

Citation 07

https://peerj.com/articles/16489/

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ

Available Sizes

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