AF/LE Purified Anti-Human CD44 Antibody[Hermes-1]
Product Specifications
Background
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
Abbreviation
CD44
Gene ID
960
UniProt
P16070
Host
Rat
Reactivity
Human
Target
CDw44; Epican; HUTCH-I; LHR; PGP-I
Clonality
Monoclonal
Clone
Hermes-1
Conjugation
None (AF/LE)
Applications
FCM; Block
Field of Research
Cell Biology; Immunology
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Citation 01
https://pubs.rsc.org/en/content/articlelanding/2020/bm/c9bm01394f
Citation 02
https://www.sciencedirect.com/science/article/pii/S0939641123002369
Recommended Usage
6
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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