Purified Anti-Human CD40 Antibody[G28.5]
Product Specifications
Background
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand) .
Abbreviation
CD40
Gene ID
958
UniProt
P25942
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD40 protein
Target
Bp50; CD40L receptor; CDw40; TNFRSF5
Clonality
Monoclonal
Clone
G28.5
Conjugation
Unconjugated
Applications
FCM
Field of Research
Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
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