AF/LE Purified Anti-Human CD40 Antibody[G28.5]

Product Specifications

Background

CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand) .

Abbreviation

CD40

Gene ID

958

UniProt

P25942

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD40 protein

Target

Bp50; CD40L receptor; CDw40; TNFRSF5

Clonality

Monoclonal

Clone

G28.5

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.