Purified Anti-Human CD20 Antibody[2H7]
Product Specifications
Background
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn) . It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
Abbreviation
CD20
Gene ID
931
UniProt
P11836
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD20 protein
Target
B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; MS4A1
Clonality
Monoclonal
Clone
2H7
Conjugation
Unconjugated
Applications
FCM
Field of Research
Costimulatory Molecules; Immunology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/rrtsck
Product MSDS
https://789.bio/eb/zXDC4O
Recommended Usage
6
Isotype
Mouse IgG2b, κ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
