PE Anti-Human CD14 Antibody[M5E2]

Product Specifications

Background

CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI) -linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

Abbreviation

CD14

Gene ID

929

UniProt

P08571

Host

Mouse

Reactivity

Human

Target

CD14; Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein

Clonality

Monoclonal

Clone

M5E2

Conjugation

Applications

FCM

Field of Research

Cell Biology; Immunology; Innate Immunity; Neuroinflammation; Neuroscience

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.cell.com/cell-reports-physical-science/fulltext/S2666-3864(25)00161-4

Citation 02

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1446710/full

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ

Available Sizes

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