AF/LE Purified Anti-Human/Mouse IL-5 Antibody[TRFK5]

Product Specifications

Background

IL-5 (Interleukin-5) is a secreted cytokine that is expressed as a covalent dimer. It is produced by activated Th2 cells, eosinophils, mast cells, and iNKT cells and promotes eosinophilic and basophilic differentiation and activation. IL-5 signals through a receptor complex containing IL-5 R alpha and the Common beta Chain/CD131 on eosinophils and basophils. Naturally occurring soluble forms of IL-5 R alpha retain the ability to bind IL-5 and limit its bioavailability.

Abbreviation

IL-5

Gene ID

16191;3567

UniProt

P05113; P04401

Host

Rat

Reactivity

Human; Mouse

Immunogen

Recombinant Mouse IL-5 protein

Target

B-cell differentiation factor I; IL-5; Interleukin-5; T-cell replacing factor; TRF

Clonality

Monoclonal

Clone

TRFK5

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.