FITC Anti-Mouse IL-10 Antibody[JES5-16E3]
Product Specifications
Background
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production) ; and promotes mast cell proliferation in combination with IL-4.
Abbreviation
IL-10
Gene ID
16153
UniProt
P18893
Host
Rat
Reactivity
Mouse
Target
CSIF; Cytokine synthesis inhibitory factor; IL-10; Interleukin-10
Clonality
Monoclonal
Clone
JES5-16E3
Conjugation
FITC
Applications
ICFCM
Field of Research
Immunology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.70147
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2b, κ
Available Sizes
Curated Selection
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