FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
Product Specifications
Background
CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells) . Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Abbreviation
CD366
Gene ID
84868
UniProt
Q8VIM0
Host
Rat
Reactivity
Mouse
Target
TIMD3; HAVcr-2; TIM3; TIMD-3
Clonality
Monoclonal
Clone
RMT3-23
Conjugation
FITC
Applications
FCM
Field of Research
Immunology; Inhibitory Molecules
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.sciencedirect.com/science/article/pii/S0378517324005830
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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