APC Anti-Mouse FcεRIα Antibody[MAR-1]
Product Specifications
Background
FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
Abbreviation
FcεRIα
Gene ID
14125
UniProt
P20489
Host
Armenian Hamster
Reactivity
Mouse
Target
Fc-epsilon RI-alpha; FcERI; Fcer1a; High affinity immunoglobulin epsilon receptor subunit alpha
Clonality
Monoclonal
Clone
MAR-1
Conjugation
APC
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
0.2 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
6
Isotype
Armenian Hamster IgG
Available Sizes
Documents
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