APC Anti-Human CD95/Fas Antibody[DX2]
Product Specifications
Background
CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand) . CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
Abbreviation
CD95
Gene ID
355
UniProt
P25445
Host
Mouse
Reactivity
Human
Target
APT1; Apo-1 antigen; FAS1; FASLG receptor; TNFRSF6; Fas
Clonality
Monoclonal
Clone
DX2
Conjugation
APC
Applications
FCM
Field of Research
Apoptosis/Tumor Suppressors/Cell Death; Cell Biology; Immunology; Neuroscience
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.sciencedirect.com/science/article/pii/S0024320522008633
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
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