FITC Anti-Human CD326/EpCAM Antibody[9C4]
Product Specifications
Background
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
Abbreviation
CD326
Gene ID
4072
UniProt
P16422
Host
Mouse
Reactivity
Human
Target
TROP1; Ep-CAM; EpCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1
Clonality
Monoclonal
Clone
9C4
Conjugation
FITC
Applications
FCM
Field of Research
Cell Biology; Immunology; Stem Cells
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/rpokap
Product MSDS
https://789.bio/eb/r1CSe9
Citation 01
https://journals.physiology.org/doi/abs/10.1152/physiolgenomics.00119.2024
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2b, κ
Available Sizes
Curated Selection
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