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APC Anti-Human CD206/MMR Antibody[15-2]

Product Specifications

Background

Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR) . It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.

Abbreviation

CD206

Gene ID

4360

UniProt

P22897

Host

Mouse

Reactivity

Human

Target

CLEC13D; CLEC13DL; MMR; MRC1L1; hMR

Clonality

Monoclonal

Clone

15-2

Conjugation

APC

Applications

FCM

Field of Research

Cell Biology; Immunology; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S1385894723066639

Citation 02

https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202401931

Citation 03

https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202407802

Citation 04

https://www.sciencedirect.com/science/article/pii/S1385894724033795

Citation 05

https://link.springer.com/article/10.1186/s13046-024-03269-4

Citation 06

https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01192-w

Citation 07

https://www.sciencedirect.com/science/article/pii/S0141813022017585

Citation 08

https://www.sciencedirect.com/science/article/pii/S2667005424000875

Citation 09

https://link.springer.com/article/10.1186/s12967-024-05149-z

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

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