FITC Anti-Human CD206/MMR Antibody[15-2]

Product Specifications

Background

Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR) . It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.

Abbreviation

CD206

Gene ID

4360

UniProt

P22897

Host

Mouse

Reactivity

Human

Target

CLEC13D; CLEC13DL; MMR; MRC1L1; hMR

Clonality

Monoclonal

Clone

15-2

Conjugation

FITC

Applications

FCM

Field of Research

Cell Biology; Immunology; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.nature.com/articles/s42003-025-07512-2

Citation 02

https://www.sciencedirect.com/science/article/pii/S0014299924008471

Citation 03

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020012/

Citation 04

https://www.tandfonline.com/doi/abs/10.1080/17501911.2024.2430166

Citation 05

https://journals.lww.com/immunotherapy-journal/fulltext/9900/15_deoxy___12,14_prostaglandin_j2_represses_immune.127.aspx

Citation 06

https://www.termedia.pl/Macrophage-M2-polarization-induced-by-ANKRD22-in-lung-adenocarcinoma-facilitates-tumor-angiogenesis,10,55909,0,1.html

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

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