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PE Anti-Human CD184/CXCR4 Antibody[12G5]

Product Specifications

Background

CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.

Abbreviation

CD184

Gene ID

7852

UniProt

P61073

Host

Mouse

Reactivity

Human

Target

FB22; Fusin; HM89; LAP-3; LCR1

Clonality

Monoclonal

Clone

12G5

Conjugation

PE

Applications

FCM

Field of Research

Cell Biology; Immunology; Innate Immunity; Neuroinflammation; Neuroscience; Neuroscience Cell Markers; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Product Datasheet

https://789.bio/ea/d0mtad

Product MSDS

https://789.bio/eb/jfjznH

Citation 01

https://www.nature.com/articles/s41467-024-47111-z

Citation 02

https://www.hindawi.com/journals/sci/2020/1498315/

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ

Available Sizes

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