PE/Cyanine5.5 Anti-Human CD161 Antibody[HP-3G10]
Product Specifications
Background
CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.
Abbreviation
CD161
Gene ID
3820
UniProt
Q12918
Host
Mouse
Reactivity
Human
Target
NKRP1A; CLEC5B; HNKR-P1a; KLRB1; NKR-P1A
Clonality
Monoclonal
Clone
HP-3G10
Conjugation
PE/Cyanine 5.5
Applications
FCM
Field of Research
Cell Biology; Immunology; Innate Immunity; Signal Transduction
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
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