APC Anti-Human CD117/c-Kit Antibody[104D2]
Product Specifications
Background
CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML) . CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.
Abbreviation
CD117
Gene ID
3815
UniProt
P10721
Host
Mouse
Reactivity
Human
Target
CD117; Kit; Mast/stem cell growth factor receptor Kit; Proto-oncogene c-Kit; SCFR; Tyrosine-protein kinase Kit; c-Kit
Clonality
Monoclonal
Clone
104D2
Conjugation
APC
Applications
FCM
Field of Research
Immunology; Stem Cells
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202402600
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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