Elab Fluor® 488 Anti-Human CD45RO Antibody[UCHL1]
Product Specifications
Background
CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
Abbreviation
CD45RO
Gene ID
5788
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
UCHL1
Conjugation
Elab Fluor®488
Applications
FCM
Field of Research
Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers; Stem Cells
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/80go40
Product MSDS
https://789.bio/eb/vHmXPC
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2a, κ
Available Sizes
Curated Selection
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