PE Anti-Mouse CD45 Antibody[30-F11]
Product Specifications
Background
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Abbreviation
CD45
Gene ID
19264
UniProt
P06800
Host
Rat
Reactivity
Mouse
Target
CD45; L-CA; Ly-5; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200
Clonality
Monoclonal
Clone
30-F11
Conjugation
PE
Applications
FCM
Field of Research
Cell Biology; Immunology; Inhibitory Molecules; Innate Immunity; Neuroscience; Neuroscience Cell Markers; Stem Cells
Concentration
0.2 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.nature.com/articles/s41419-022-05069-0
Citation 02
https://www.nature.com/articles/s41419-023-06408-5
Citation 03
https://link.springer.com/article/10.1007/s00262-024-03692-8
Recommended Usage
6
Isotype
Rat IgG2b, κ
Available Sizes
Documents
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