PE Anti-Mouse CD45 Antibody[30-F11]

Product Specifications

Background

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Abbreviation

CD45

Gene ID

19264

UniProt

P06800

Host

Rat

Reactivity

Mouse

Target

CD45; L-CA; Ly-5; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200

Clonality

Monoclonal

Clone

30-F11

Conjugation

Applications

FCM

Field of Research

Cell Biology; Immunology; Inhibitory Molecules; Innate Immunity; Neuroscience; Neuroscience Cell Markers; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202425739

Citation 02

https://pubs.acs.org/doi/abs/10.1021/acsnano.4c11658

Citation 03

https://www.sciencedirect.com/science/article/pii/S0142961224000085

Citation 04

https://aacrjournals.org/cancerimmunolres/article-abstract/doi/10.1158/2326-6066.CIR-22-0318/710112

Citation 05

https://onlinelibrary.wiley.com/doi/abs/10.1111/acel.14374

Citation 06

https://link.springer.com/article/10.1007/s00262-021-02894-8

Citation 07

https://elifesciences.org/articles/100002

Citation 08

https://www.nature.com/articles/s41541-025-01132-x

Citation 09

https://www.tandfonline.com/doi/abs/10.2147/DDDT.S503930

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2b, κ

Available Sizes

Documents

Product Datasheet

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