AF/LE Purified Anti-Human CD1a Antibody[OKT-6]
Product Specifications
Background
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.
Abbreviation
CD1a
Gene ID
909
UniProt
P06126
Host
Mouse
Reactivity
Human
Target
R4; CD 1a; CD1A ; T-cell surface glycoprotein CD1a; T6
Clonality
Monoclonal
Clone
OKT-6
Conjugation
None (AF/LE)
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Documents
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