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AF/LE Purified Anti-Human CD1a Antibody[OKT-6]

Product Specifications

Background

CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.

Abbreviation

CD1a

Gene ID

909

UniProt

P06126

Host

Mouse

Reactivity

Human

Target

R4; CD 1a; CD1A ; T-cell surface glycoprotein CD1a; T6

Clonality

Monoclonal

Clone

OKT-6

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Recommended Usage

6

Isotype

Mouse IgG1, κ

Available Sizes

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