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FITC Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody[RB6-8C5]

Product Specifications

Background

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI) -linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

Abbreviation

Ly-6G

Gene ID

546644;17067

UniProt

P35461; P0CW03

Host

Rat

Reactivity

Mouse

Target

Gr-1; Gr1; Ly-6G/Ly-6C; Ly6G/Ly6C

Clonality

Monoclonal

Clone

RB6-8C5

Conjugation

FITC

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202419583

Citation 02

https://www.sciencedirect.com/science/article/pii/S1748013223001299

Citation 03

https://www.nature.com/articles/s41467-024-47111-z

Citation 04

https://pubs.acs.org/doi/abs/10.1021/acsami.4c09925

Citation 05

https://www.hindawi.com/journals/omcl/2023/2894695/

Citation 06

https://mct.aacrjournals.org/content/19/11/2340.abstract

Citation 07

https://pmc.ncbi.nlm.nih.gov/articles/PMC11963557/

Citation 08

https://www.mdpi.com/2218-273X/14/9/1147

Citation 09

https://www.sciencedirect.com/science/article/pii/S1567576924006489

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2b, κ

Available Sizes

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