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AF/LE Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody[RB6-8C5]

Product Specifications

Background

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI) -linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

Abbreviation

Ly-6G/Ly-6C (Gr-1)

UniProt

P35461; P0CW03

Host

Rat

Reactivity

Mouse

Immunogen

Recombinant Mouse Gr-1 protein

Target

Gr-1; Gr1; Ly-6G/Ly-6C; Ly6G/Ly6C

Clonality

Monoclonal

Clone

RB6-8C5

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Innate Immunity

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Recommended Usage

6

Isotype

Rat IgG2b, κ

Available Sizes

Frequently Asked Questions

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