FITC Anti-Mouse CD49b/pan-NK cells Antibody[DX5]
Product Specifications
Background
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection) . DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Abbreviation
CD49b
Gene ID
16398
UniProt
Q62469
Host
Rat
Reactivity
Mouse
Target
CD49 antigen-like family member B; CD49b; Collagen receptor; GPIa; Integrin alpha-2; Platelet membrane glycoprotein Ia; VLA-2 subunit alpha; pan-NK cells
Clonality
Monoclonal
Clone
DX5
Conjugation
FITC
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Immunology; Innate Immunity
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo01547h
Recommended Usage
6
Isotype
Rat IgM, κ
Available Sizes
Documents
Curated Selection
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