PE Anti-Mouse CD119 Antibody[GR-20]
Product Specifications
Background
CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
Abbreviation
CD119
Gene ID
15979
UniProt
P15261
Host
Rat
Reactivity
Mouse
Target
CD119; IFN-gamma-R-alpha; IFN-gamma-R1; Ifngr1; Interferon gamma receptor 1
Clonality
Monoclonal
Clone
GR-20
Conjugation
PE
Applications
FCM
Field of Research
Immunology
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00433-6
Citation 02
https://www.science.org/doi/abs/10.1126/sciadv.ado6798
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2a, κ
Available Sizes
Documents
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