FITC Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]
Product Specifications
Background
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4) . CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Abbreviation
CD183
Gene ID
12766
UniProt
O88410
Host
Armenian Hamster
Reactivity
Mouse
Target
C-X-C chemokine receptor type 3; CD183/CXCR3; CXC-R3; CXCR-3; Cxcr3; IP-10 receptor; Interferon-inducible protein 10 receptor
Clonality
Monoclonal
Clone
CXCR3-173
Conjugation
FITC
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Armenian Hamster IgG
Available Sizes
Documents
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