AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]

Product Specifications

Background

CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4) . CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Abbreviation

CD183/CXCR3

Gene ID

12766

UniProt

O88410

Host

Armenian Hamster

Reactivity

Mouse

Target

C-X-C chemokine receptor type 3; CD183/CXCR3; CXC-R3; CXCR-3; Cxcr3; IP-10 receptor; Interferon-inducible protein 10 receptor

Clonality

Monoclonal

Clone

CXCR3-173

Conjugation

None (AF/LE)

Applications

FCM; Block

Field of Research

Immunology; Innate Immunity

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.