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PE/Cyanine7 Anti-Human HLA-DR Antibody[L243]

Product Specifications

Background

HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

Abbreviation

HLA-DR

Gene ID

3122;3123

UniProt

P01903; P01911

Host

Mouse

Reactivity

Human

Target

DRA/DRB1; HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain; HLA-DRA1/DRB1; MHC class II antigen DRA

Clonality

Monoclonal

Clone

L243

Conjugation

PE/Cyanine 7

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.frontiersin.org/articles/10.3389/fcimb.2021.785166/full?utm_source=dlvr.it&utm_medium=twitter

Citation 02

https://www.sciencedirect.com/science/article/pii/S0024320525003480

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ

Available Sizes

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