APC Anti-Human HLA-DR Antibody[L243]
Product Specifications
Background
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
Abbreviation
HLA-DR
Gene ID
3122;3123
UniProt
P01903; P01911
Host
Mouse
Reactivity
Human
Target
DRA/DRB1; HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain; HLA-DRA1/DRB1; MHC class II antigen DRA
Clonality
Monoclonal
Clone
L243
Conjugation
APC
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.nature.com/articles/s41541-024-01060-2
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2a, κ
Available Sizes
Documents
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