AF/LE Purified Anti-Human HLA-DR Antibody[L243]
Selected Variant
E-AB-F11110-01
Size: 100 µg
Product Specifications
Background
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
Abbreviation
HLA-DR
Gene ID
3122;3123
UniProt
P01903; P01911
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human HLA-DR protein
Target
DRA/DRB1; HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain; HLA-DRA1/DRB1; MHC class II antigen DRA
Clonality
Monoclonal
Clone
L243
Conjugation
None (AF/LE)
Applications
FCM
Field of Research
Immunology; Innate Immunity
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Recommended Usage
6
Isotype
Mouse IgG2a, κ
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