Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PE Anti-Human CD8a Antibody[OKT-8]

Product Specifications

Background

CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers) . CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

Abbreviation

CD8

Gene ID

925

UniProt

P01732

Host

Mouse

Reactivity

Human

Target

CD8A; MAL; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2

Clonality

Monoclonal

Clone

OKT-8

Conjugation

PE

Applications

FCM

Field of Research

Immunology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.cell.com/cell-reports-physical-science/fulltext/S2666-3864(25)00161-4

Citation 02

https://onlinelibrary.wiley.com/doi/abs/10.1002/jbt.23761

Citation 03

https://pmc.ncbi.nlm.nih.gov/articles/PMC11664623/

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-Human XCR1 Antibody (11H2), PerCP
MBS1584244-01 50 Tests

Anti-Human XCR1 Antibody (11H2), PerCP

Sign In for Pricing
View Details
Anti-Human XCR1 Antibody (11H2), PerCP
MBS1584244-02 100 Tests

Anti-Human XCR1 Antibody (11H2), PerCP

Sign In for Pricing
View Details
Anti-Human XCR1 Antibody (11H2), PerCP
MBS1584244-03 5x 100 Tests

Anti-Human XCR1 Antibody (11H2), PerCP

Sign In for Pricing
View Details
Anti-HDAC11 Antibody (R2N44)
RHN04203 100 μg

Anti-HDAC11 Antibody (R2N44)

Sign In for Pricing
View Details
PODXL Rabbit pAb
MBS8543728-01 0.1 mL

PODXL Rabbit pAb

Sign In for Pricing
View Details
PODXL Rabbit pAb
MBS8543728-02 0.1 mL (AF405L)

PODXL Rabbit pAb

Sign In for Pricing
View Details