APC Anti-Human CD4 Antibody[RPA-T4]

Product Specifications

Background

CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7) .

Abbreviation

CD4

Gene ID

920

UniProt

P01730

Host

Mouse

Reactivity

Human

Target

CD4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4

Clonality

Monoclonal

Clone

RPA-T4

Conjugation

APC

Applications

FCM

Field of Research

Immunology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.nature.com/articles/s41467-025-60448-3

Citation 02

https://www.cell.com/cell-reports-physical-science/fulltext/S2666-3864(25)00161-4

Citation 03

https://www.sciencedirect.com/science/article/pii/S0024320525003480

Citation 04

https://www.tandfonline.com/doi/abs/10.1080/08820139.2024.2385992

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

Documents

Product Datasheet

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