AF/LE Purified Anti-Mouse CD3ε Antibody[145-2C11]
Product Specifications
Background
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Abbreviation
CD3ε
Gene ID
12501
UniProt
P22646
Host
Armenian Hamster
Reactivity
Mouse
Immunogen
Recombinant Mouse CD3ε protein
Target
CD3E; CD3e; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E
Clonality
Monoclonal
Clone
145-2C11
Conjugation
None (AF/LE)
Applications
FCM
Field of Research
Immunology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Citation 01
https://www.sciencedirect.com/science/article/pii/S156757692301247X
Citation 02
https://www.sciencedirect.com/science/article/pii/S1567576919315838
Recommended Usage
6
Isotype
Armenian Hamster IgG
Available Sizes
Documents
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