FITC Anti-Human/Mouse CD44 Antibody[IM7]

Product Specifications

Background

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Abbreviation

CD44

Gene ID

12505;960

UniProt

P15379; P16070

Host

Rat

Reactivity

Human; Mouse

Target

MDU2MDU3MIC4; CD44; CD44 antigen; CDw44; Epican; LHR; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I

Clonality

Monoclonal

Clone

IM7

Conjugation

FITC

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Immunology; Stem Cells

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://pubs.acs.org/doi/abs/10.1021/acsnano.4c07213

Citation 02

https://www.sciencedirect.com/science/article/pii/S0142961225000158

Citation 03

https://aacrjournals.org/cancerimmunolres/article-abstract/doi/10.1158/2326-6066.CIR-22-0318/710112

Citation 04

https://www.sciencedirect.com/science/article/pii/S0142961225003102

Citation 05

https://www.sciencedirect.com/science/article/pii/S0168365925001749

Citation 06

https://www.sciencedirect.com/science/article/pii/S1742706124006329

Citation 07

https://pubs.acs.org/doi/abs/10.1021/acs.biomac.1c01076

Citation 08

https://link.springer.com/article/10.1007/s00262-021-02894-8

Citation 09

https://www.nature.com/articles/s41541-025-01132-x

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2b, κ

Available Sizes

Documents

Product Datasheet

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