Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12]
Product Specifications
Background
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-) . CD90.2 is a glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Abbreviation
CD90.2/Thy1.2
Host
Rat
Reactivity
Mouse
Immunogen
Recombinant Mouse CD90.2 protein
Target
CD90.2; Thy-1.2; Thy-1.2 antigen; Thy-1.2 membrane glycoprotein; Thy1.2
Clonality
Monoclonal
Clone
30H12
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Rat IgG2b, κ
Available Sizes
Documents
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