APC Anti-Mouse CD117/c-Kit Antibody[2B8]
Product Specifications
Background
CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR) . It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor) . CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Abbreviation
CD117
Gene ID
16590
UniProt
P05532
Host
Rat
Reactivity
Mouse
Target
CD117; Kit; Mast/stem cell growth factor receptor Kit; Proto-oncogene c-Kit; SCFR; Tyrosine-protein kinase Kit; c-Kit
Clonality
Monoclonal
Clone
2B8
Conjugation
APC
Applications
FCM
Field of Research
Immunology; Stem Cells
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://pmc.ncbi.nlm.nih.gov/articles/PMC11963557/
Citation 02
https://www.mdpi.com/2218-273X/14/9/1147
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2b, κ
Available Sizes
Documents
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