Purified Anti-Mouse CD117/c-Kit Antibody[2B8]
Product Specifications
Background
CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR) . It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor) . CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Abbreviation
CD117/c-Kit
Gene ID
16590
UniProt
P05532
Host
Rat
Reactivity
Mouse
Target
CD117; Kit; Mast/stem cell growth factor receptor Kit; Proto-oncogene c-Kit; SCFR; Tyrosine-protein kinase Kit
Clonality
Monoclonal
Clone
2B8
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Stem Cells
Concentration
≥ 1 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Rat IgG2b, κ
Available Sizes
Documents
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