AF/LE Purified Anti-Mouse CD117/c-Kit Antibody[2B8]

Product Specifications

Background

CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR) . It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor) . CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Abbreviation

CD117/c-Kit

Gene ID

16590

UniProt

P05532

Host

Rat

Reactivity

Mouse

Target

CD117; Kit; Mast/stem cell growth factor receptor Kit; Proto-oncogene c-Kit; SCFR; Tyrosine-protein kinase Kit

Clonality

Monoclonal

Clone

2B8

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Stem Cells

Concentration

≥ 1 mg/mL

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.