AF/LE Purified Anti-Mouse CD106 Antibody[M/K-2.7]

Product Specifications

Background

CD106 is a 110 kD glycosylphosphatidylinositol (GPI) -linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin) .

Abbreviation

CD106

UniProt

P29533

Host

Rat

Reactivity

Mouse

Target

CD106; V-CAM 1; VCAM-1; Vascular cell adhesion protein 1; Vcam1

Clonality

Monoclonal

Clone

M/K-2.7

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Immunology; Neuroinflammation; Neuroscience; Stem Cells

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.