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APC Anti-Human CD64 Antibody[10.1]

Product Specifications

Background

CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC) .

Abbreviation

CD64

Gene ID

2209

UniProt

P12314

Host

Mouse

Reactivity

Human

Target

CD64; CD64A/B/C; FCGR1A/B/C; Fc fragment of IgG high affinity Ia/b/c receptor; Fc gamma RI; IGFR 1

Clonality

Monoclonal

Clone

10.1

Conjugation

APC

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S0344033825001025

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

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