Purified Anti-Human CD64 Antibody[10.1]
Product Specifications
Background
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC) .
Abbreviation
CD64
Gene ID
2209
UniProt
P12314
Host
Mouse
Reactivity
Human
Target
CD64; CD64A/B/C; FCGR1A/B/C; Fc fragment of IgG high affinity Ia/b/c receptor; Fc gamma RI; IGFR 1
Clonality
Monoclonal
Clone
10.1
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
≥ 1 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Citation 01
https://www.sciencedirect.com/science/article/pii/S0927775724003820
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Documents
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